Kidney Transplant Chains Amplify Benefit of Nondirected Donors
نویسندگان
چکیده
منابع مشابه
Kidney transplant chains amplify benefit of nondirected donors.
IMPORTANCE Despite the potential for altruistic nondirected donors (NDDs) to trigger multiple transplants through nonsimultaneous transplant chains, concerns exist that these chains siphon NDDs from the deceased donor wait list and that donors within chains might not donate after their partner receives a transplant. OBJECTIVE To determine the number of transplantations NDDs trigger through ch...
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Organ transplantation is a highly complex decision process that requires expert decisions. The major problem in a transplantation procedure is the possibility of the receiver’s immune system attack and destroy the transplanted tissue. It is therefore of capital importance to find a donor with the highest possible compatibility with the receiver, and thus reduce rejection. Finding a good donor i...
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Kidneys from nondirected donors (NDDs) have historically been allocated directly to the deceased donor wait list (DDWL). Recently, however, NDDs have participated in kidney exchange (KE) procedures, including KE 'chains', which have received considerable media attention. This increasing application of KE chains with NDD participation has occurred with limited ethical analysis and without ethica...
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BACKGROUND A report from a high-volume single center indicated a survival benefit of receiving a kidney transplant from an HLA-incompatible live donor as compared with remaining on the waiting list, whether or not a kidney from a deceased donor was received. The generalizability of that finding is unclear. METHODS In a 22-center study, we estimated the survival benefit for 1025 recipients of ...
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ژورنال
عنوان ژورنال: JAMA Surgery
سال: 2013
ISSN: 2168-6254
DOI: 10.1001/2013.jamasurg.25